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pronephric glomerulus

^ http://purl.obolibrary.org/obo/UBERON_0004739


The glomus forms from the splanchnic intermediate mesoderm and is the vascularized filtration unit, filtering the blood before it enters the tubules. The glomus is external to the nephron and extends over more than one body segment. [ http://amigo.geneontology.org/amigo/term/GO:0072013 XAO:0000318 http://www.ncbi.nlm.nih.gov/pubmed/9268568 http://www.ncbi.nlm.nih.gov/pubmed/10572058 http://www.ncbi.nlm.nih.gov/pubmed/15647339 GOC:mtg_kidney_jan10 http://dx.doi.org/10.1371/journal.pone.0099864 ]

Synonyms: glomerulus of pronephros

Term info

database cross reference
  • ZFA:0001557
  • TAO:0001557
  • XAO:0000318
  • AAO:0011049
  • SCTID:360548001
  • VHOG:0001237
plural term
pronephric glomeruli [ VHOG:0001237 ]

plural term
glomera [ XAO:0000318 ]

UBPROP 0000001

Paired highly vascularized portion of the pronephros. Left and right glomeruli are fused at the midline. Begins to function between 40 and 48hpf. Drummond, 2000.[TAO]

UBPROP 0000003

The teleost pronephros shares many essential features with the amphibian pronephros including its derivation from mesoderm associated with the coelom and the derivation of the glomerular blood supply from the medial dorsal aorta. However, unlike the pronephros of amphibians, which have an external glomus and tubules with nephrostomes open to the coelom, the mature teleost pronephros has no connection to the body cavity and instead functions as a closed system (reference 1); This variation in nephron types [with external glomeruli that open into the coelom and with internal glomeruli that do not connect with the coelom] and their pattern of distribution suggest an evolutionary sequence. Ancestral craniates probably had an external glomerulus and nephrostomes, as do the first few to develop in very primitive craniates. (...) The mechanism would become more efficient as the coelomic recess into which each glomerulus discharged became a part of the tubule, that is, grew around the glomerulus as a renal capsule. The glomerulus becomes internal. The nephrostomes were lost during subsequent evolution, leaving the type of renal tubule found in most vertebrates (reference 2).[well established][VHOG]

UBPROP 0000012

GO treats glomus and pronephric glomerulus differently

curator note

a glomus differs from a glomerulus in that each vascular glomus services several tubules

has related synonym

corpuscle, pronephric glomus, pronephric glomeruli, pronephric glomera, glomera

has alternative id

UBERON:0004191

id

UBERON:0004739