JSON

thymus primordium

^ http://purl.obolibrary.org/obo/UBERON_0005562


A small outgrowth of the pharyngeal epithelium that is the site of lymphocyte cell production[ZFA]. [PMID]. [ ZFA:0001077 ]

Synonyms: thymic rudiment, thymic primordium

Term info

database cross reference
  • TAO:0001077
  • EMAPA:17523
  • EHDAA2:0002023
  • EHDAA:2969
  • EFO:0003622
  • ZFA:0001077
Subsets

efo_slim, vertebrate_core

UBPROP 0000001

A small outgrowth of the pharyngeal epithelium that is the site of lymphocyte cell production. Willett et al, 1999.[TAO]

UBPROP 0000008

variability of developmental origin: In fish, thymic primordia are generated by all the pouches except the first. However, in avians the thymus arises from pouches 3 and 4, whereas in humans it is only generated by the third pouch[PMID:16313389] The thymus arises from the second pouch in frogs, 2-6 in cartilaginous fish, 2-3 in reptiles, 3 or 4 in bony fish, birds and mammals. The final number is variable - 5 paired organs in sharks, 4 in caecilians, 3 in urodeles, 1 in many teleost, anurans and many mammals

editor note

we follow Kardong table 13.1 in having some developmental contribution of pouch 4 in mammals, but this isn't reflected in EHDAA2. Consider adding distinct term for mesenchyme (see EHDAA2), to indicate NC constribution.

id

UBERON:0005562