pharyngeal pouch 4
A pharyngeal pouch between pharyngeal arch 4 and arch 5 or 6 (a fifth arch never establishes in amniotes). [ http://www.ncbi.nlm.nih.gov/pubmed/16313389 http://en.wikipedia.org/wiki/Pharyngeal_pouch_(embryology)#Fourth_pouch http://openisbn.com/search.php?q=0124020607&isbn=1/ ]
Synonyms: pharyngeal pouches 4, 4th arch branchial pouch, 4th branchial pouch, 4th pharyngeal pouch endoderm, fourth arch pharyngeal pouch, visceral pouch 4, fourth branchial pouch, fourth visceral pouch, 4th arch branchial pouch endoderm
Term info
- EHDAA2:0000091
- EFO:0003637
- XAO:0000254
- UMLS:C0231071 (ncithesaurus:Fourth_Pharyngeal_Pouch)
- VHOG:0000971
- NCIT:C34181
- ZFA:0001134
- TAO:0001134
- RETIRED_EHDAA2:0000090
- AAO:0011117
- VHOG:0000578
- FMA:295688
- EMAPA:16766
- SCTID:362858001
- Wikipedia:Pharyngeal_pouch_(embryology)#Fourth_pouch
efo_slim, pheno_slim, vertebrate_core
Fourth of the pharyngeal (endodermal) evaginations between the visceral arches from which the Eustachian tube is derived; pouches 2-4 open as gill slits.[AAO], A pouch that is situated between the 4th and 5th pharyngeal arch. [ISBN:0124020607][VHOG]
A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down. The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal pouches.[well established][VHOG]
Derivatives include: superior parathyroid glands and ultimobranchial body which forms the parafollicular C-Cells of the thyroid gland. Musculature and cartilage of larynx (along with the sixth pharyngeal pouch)[WP] in most mammals, excluding rodents, the dorsal part of each fourth pouch develops into a superior parathyroid gland (parathyroid IV), which lies on the dorsal surface of the thyroid gland (the parathyroid glands derived from the third pouches descend with the thymus and are carried to a more inferior position than the parathyroid glands that are derived from the fourth pouches); the elongated ventral part of each fourth pouch develops into the ultimopharyngeal body, which fuses with the thyroid gland, giving rise to the calcitonin-producing parafollicular or C-cells of the thyroid gland. In the mouse, but also in the rat and hamster, the dorsal fourth pouch does not generate a parathyroid. Thus, rodents develop only one pair of parathyroid glands.
fourth pharyngeal pouch
uberon
UBERON:0007125
pharyngeal pouch 4
Term relations
- pharyngeal pouch and overlaps some pharyngeal arch 4 and overlaps some pharyngeal arch 5