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inner cell mass derived epiblast

^ http://purl.obolibrary.org/obo/UBERON_0008780

An embryonic structure that is derived from the inner cell mass and lies above the hypoblast and gives rise to the three primary germ layers. [ MP:0003886 ]

Term info

database cross reference
  • EMAPA:16050
  • UMLS:C1516906 (ncithesaurus:Epiblast)
  • EHDAA:75
  • EHDAA:42
  • NCIT:C34164
  • EHDAA2:0000444
Subsets

pheno_slim, early_development

comment

The epiblast cells (appearing on day 8 of human embryonic development) make up a columnar epithelium with dense microvilli on the apical surface. During gastrulation, the epiblast cells undergo epithelial-to-mesenchymal transition and delaminate to become the loose mesenchyme of the primitive streak. The epiblast is present in postimplantation mouse embryos between E5.5-E7.5.

has related synonym

embryonic epiblast

id

UBERON:0008780