Term info
database cross reference
- MSH:D018455
- UMLS:C0242666
- SNOMEDCT_US:1563006
- UMLS:C4025284
comment
Protein S functions as a cofactor to Protein C in the inactivation of Factors Va and VIIIa in the coagulation pathway. Therefore, a defect in protein S is associated with an increased risk of thrombosis.
definition
An abnormality of coagulation related to a decreased concentration of vitamin K-dependent protein S. Protein S is a cofactor of protein C.
has narrow synonym
Protein S deficiency
id
HP:0004855