oral cavity squamous cell carcinoma
http://purl.obolibrary.org/obo/MONDO_0004958
A squamous cell carcinoma arising from the oral cavity. It affects predominantly adults in their fifth and sixth decades of life and is associated with alcohol and tobacco use. Human papillomavirus is present in approximately half of the cases. It is characterized by a tendency to metastasize early to the lymph nodes. When the tumor is small, patients are often asymptomatic. Physical examination may reveal erythematous or white lesions or plaques. The majority of patients present with signs and symptoms of locally advanced disease including mucosal ulceration, pain, difficulty with speaking, chewing, and swallowing, bleeding, weight loss, and neck swelling. Patients may also present with swollen neck lymph nodes without any symptoms from the oropharyngeal tumor. The most significant prognostic factors are the size of the tumor and the lymph nodes status. [ NCIT:C4833 ]
Term info
- SCTID:307502000 (MONDO:equivalentTo)
- GARD:0007263 (MONDO:equivalentTo)
- ONCOTREE:OCSC (MONDO:equivalentTo)
- DOID:0050866 (MONDO:equivalentTo)
- Orphanet:502363 (MONDO:equivalentTo)
- UMLS:C0585362 (NCIT:C4833)
- NCIT:C4833 (MONDO:equivalentTo)
- EFO:0000199 (MONDO:equivalentTo)
gard_rare, ordo_disease
A squamous cell carcinoma arising from the oral cavity. It affects predominantly adults in their fifth and sixth decades of life and is associated with alcohol and tobacco use. Human papillomavirus is present in approximately half of the cases. It is characterized by a tendency to metastasize early to the lymph nodes. When the tumor is small, patients are often asymptomatic. Physical examination may reveal erythematous or white lesions or plaques. The majority of patients present with signs and symptoms of locally advanced disease including mucosal ulceration, pain, difficulty with speaking, chewing, and swallowing, bleeding, weight loss, and neck swelling. Patients may also present with swollen neck lymph nodes without any symptoms from the oropharyngeal tumor. The most significant prognostic factors are the size of the tumor and the lymph nodes status.
http://linkedlifedata.com/resource/umls/id/C0585362, http://purl.obolibrary.org/obo/DOID_0050866, http://purl.obolibrary.org/obo/Orphanet_502363, http://purl.obolibrary.org/obo/NCIT_C4833, http://identifiers.org/snomedct/307502000
mouth scc, squamous cell carcinoma of mouth, oral cavity squamous cell cancer, scc of the mouth, squamous cell carcinoma of oral cavity, scc of mouth, squamous cell carcinoma of the oral cavity, oral cavity scc, mouth squamous cell carcinoma, squamous cell carcinoma of the mouth, scc of the oral cavity, scc of oral cavity, oral cavity squamous cell carcinoma
OCSC, oral squamous cell carcinoma
MONDO:0004958
https://rarediseases.info.nih.gov/diseases/7263/oral-squamous-cell-carcinoma