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large cell neuroendocrine carcinoma

^ http://purl.obolibrary.org/obo/MONDO_0005057

A usually aggressive carcinoma composed of large malignant cells which display neuroendocrine characteristics. It is characterized by the presence of high mitotic activity and necrotic changes. The vast majority of cases are positive for neuron-specific enolase. Representative examples include lung, breast, cervical, and thymic neuroendocrine carcinomas. [ NCIT:C6875 ]

Term info

database cross reference
  • EFO:0000563 (MONDO:equivalentTo)
  • ONCOTREE:LUNE (MONDO:equivalentTo)
  • ICDO:8013/3 (NCIT:C6875)
  • NCIT:C6875 (MONDO:exact-label-match)
  • DOID:0050872 (MONDO:equivalentTo)
  • UMLS:C1265996 (NCIT:C6875)
abbreviation
LCNEC [ NCIT:C6875 ]

definition

A usually aggressive carcinoma composed of large malignant cells which display neuroendocrine characteristics. It is characterized by the presence of high mitotic activity and necrotic changes. The vast majority of cases are positive for neuron-specific enolase. Representative examples include lung, breast, cervical, and thymic neuroendocrine carcinomas.

exactMatch

http://purl.obolibrary.org/obo/NCIT_C6875, http://purl.obolibrary.org/obo/DOID_0050872, http://linkedlifedata.com/resource/umls/id/C1265996

has exact synonym

large-cell neuroendocrine carcinoma, large cell NEC, LCNEC, large cell neuroendocrine carcinoma

id

MONDO:0005057