celiac disease
http://purl.obolibrary.org/obo/MONDO_0005130
An autoimmune genetic disorder with an unknown pattern of inheritance that primarily affects the digestive tract. It is caused by intolerance to dietary gluten. Consumption of gluten protein triggers an immune response which damages small intestinal villi and prevents adequate absorption of nutrients. Clinical signs include abdominal cramping, diarrhea or constipation and weight loss. If untreated, the clinical course may progress to malnutrition, anemia, osteoporosis and an increased risk of intestinal malignancies. However, the prognosis is favorable with successful avoidance of gluten in the diet. [ NCIT:C26714 ]
Term info
- ICD10CM:K90.0 (MONDO:equivalentTo)
- ICD9:579.0 (MONDO:i2s)
- UMLS:C0007570 (NCIT:C26714)
- DOID:10608 (MONDO:equivalentTo)
- GARD:0011998 (MONDO:equivalentTo)
- NCIT:C26714 (MONDO:exact-label-match)
- SCTID:396331005 (MONDO:equivalentTo)
- EFO:0001060 (MONDO:equivalentTo)
- MESH:D002446 (MONDO:equivalentTo)
- OMIMPS:212750 (MONDO:equivalentTo)
- Orphanet:555 (MONDO:equivalentTo)
An autoimmune genetic disorder with an unknown pattern of inheritance that primarily affects the digestive tract. It is caused by intolerance to dietary gluten. Consumption of gluten protein triggers an immune response which damages small intestinal villi and prevents adequate absorption of nutrients. Clinical signs include abdominal cramping, diarrhea or constipation and weight loss. If untreated, the clinical course may progress to malnutrition, anemia, osteoporosis and an increased risk of intestinal malignancies. However, the prognosis is favorable with successful avoidance of gluten in the diet.
http://purl.obolibrary.org/obo/DOID_10608, http://identifiers.org/mesh/D002446, http://linkedlifedata.com/resource/umls/id/C0007570, http://purl.obolibrary.org/obo/Orphanet_555, https://omim.org/phenotypicSeries/PS212750, http://identifiers.org/snomedct/396331005, http://purl.bioontology.org/ontology/ICD10CM/K90.0, http://purl.obolibrary.org/obo/NCIT_C26714
idiopathic steatorrhea, coeliac disease, gluten intolerance, non tropical sprue, gluten-induced enteropathy, celiac sprue
MONDO:0005130
Term relations
- hereditary disease
- malabsorption syndrome
- small intestine disorder
- autoimmune disorder of gastrointestinal tract
- celiac disease, susceptibility to, 5
- celiac disease, susceptibility to, 6
- celiac disease, susceptibility to, 10
- celiac disease, susceptibility to, 12
- celiac disease, susceptibility to, 11
- celiac disease, susceptibility to, 13
- celiac disease, susceptibility to, 7
- celiac disease, susceptibility to, 9
- celiac disease, susceptibility to, 8
- celiac disease, susceptibility to, 4
- celiac disease, susceptibility to, 3
- celiac disease, susceptibility to, 2
- celiac disease, susceptibility to, 1