JSON

choriocarcinoma

^ http://purl.obolibrary.org/obo/MONDO_0005207


An aggressive malignant tumor arising from trophoblastic cells. The vast majority of cases arise in the uterus and represent gestational choriocarcinomas that derive from placental trophoblastic cells. Approximately half of the cases develop from a complete hydatidiform mole. A minority of cases arise in the testis or the ovaries. There is often marked elevation of human chorionic gonadotropin (hCG) in the blood. Choriocarcinomas disseminate rapidly through the hematogenous route; the lungs are most frequently affected. [ NCIT:C2948 ]

Term info

database cross reference
  • ICDO:9100/3 (NCIT:C2948)
  • HP:0100768 (MONDO:otherHierarchy)
  • SCTID:188188009 (MONDO:equivalentTo)
  • EFO:0002893 (MONDO:equivalentTo)
  • ONCOTREE:BCCA (MONDO:equivalentTo)
  • DOID:3594 (MONDO:equivalentTo)
  • NCIT:C2948 (MONDO:equivalentTo)
  • UMLS:C0008497 (NCIT:C2948)
  • MESH:D002822 (MONDO:equivalentTo)
  • GARD:0006059 (MONDO:shared-umls-xref)
IAO 0000589

choriocarcinoma (disease)

comment

Editor note: TODO check classification w.r.t carcinoma

definition

An aggressive malignant tumor arising from trophoblastic cells. The vast majority of cases arise in the uterus and represent gestational choriocarcinomas that derive from placental trophoblastic cells. Approximately half of the cases develop from a complete hydatidiform mole. A minority of cases arise in the testis or the ovaries. There is often marked elevation of human chorionic gonadotropin (hCG) in the blood. Choriocarcinomas disseminate rapidly through the hematogenous route; the lungs are most frequently affected.

exactMatch

http://purl.obolibrary.org/obo/NCIT_C2948, http://purl.obolibrary.org/obo/DOID_3594, http://identifiers.org/mesh/D002822, http://linkedlifedata.com/resource/umls/id/C0008497, http://identifiers.org/snomedct/188188009

excluded subClassOf

http://purl.obolibrary.org/obo/MONDO_0002178, http://purl.obolibrary.org/obo/MONDO_0004970

has exact synonym

chorion carcinoma, choriocarcinoma (disease), chorioblastoma, chorionic carcinoma, chorioepithelioma, choriocarcinoma, choriocarcinoma, malignant

id

MONDO:0005207