carcinoid tumor
http://purl.obolibrary.org/obo/MONDO_0005369
A slow growing neuroendocrine tumor, composed of uniform, round, or polygonal cells having monotonous, centrally located nuclei and small nucleoli, infrequent mitoses, and no necrosis. The tumor may show a variety of patterns, such as solid, trabecular, and acinar. Electron microscopy shows small secretory granules. Immunohistochemical studies reveal NSE, as well as chromogranin immunoreactivity. Malignant histology (cellular pleomorphism, hyperchromatic nuclei, prominent nucleoli, necrosis, and mitoses) can occasionally be seen. Such cases may have an aggressive clinical course. Gastrointestinal tract and lung are common sites of involvement. [ NCIT:C2915 ]
Term info
- SCTID:443492008 (MONDO:equivalentTo)
- ICD9:209.60 (MONDO:i2s)
- ICDO:8240/3 (NCIT:C2915)
- MESH:D002276 (MONDO:equivalentTo)
- EFO:0004243 (MONDO:equivalentTo)
- GARD:0009316 (MONDO:shared-umls-xref)
- ICDO:8241/3 (NCIT:C2915)
- NCIT:C2915 (MONDO:equivalentTo)
- HP:0100570 (MONDO:otherHierarchy)
carcinoid tumor (disease)
Editor note: In NCIT all carcinoid tumors are grade 1, but the name is sometimes used more broadly in other sources
A slow growing neuroendocrine tumor, composed of uniform, round, or polygonal cells having monotonous, centrally located nuclei and small nucleoli, infrequent mitoses, and no necrosis. The tumor may show a variety of patterns, such as solid, trabecular, and acinar. Electron microscopy shows small secretory granules. Immunohistochemical studies reveal NSE, as well as chromogranin immunoreactivity. Malignant histology (cellular pleomorphism, hyperchromatic nuclei, prominent nucleoli, necrosis, and mitoses) can occasionally be seen. Such cases may have an aggressive clinical course. Gastrointestinal tract and lung are common sites of involvement.
http://purl.obolibrary.org/obo/NCIT_C2915, http://identifiers.org/mesh/D002276, http://identifiers.org/snomedct/443492008
NET G1, carcinoid tumor, neuroendocrine tumor G1, neuroendocrine neoplasm G1, carcinoid, carcinoid tumor (disease)
MONDO:0005369