yolk sac tumor
http://purl.obolibrary.org/obo/MONDO_0005744
A non-seminomatous malignant germ cell tumor composed of primitive germ cells. It is the most common malignant germ cell tumor in the pediatric population. It occurs in the infant testis, ovary, sacrococcygeal region, vagina, uterus, prostate, abdomen, liver, retroperitoneum, thorax, and pineal/third ventricle. The tumor mimics the yolk sac of the embryo and produces alpha-fetoprotein (AFP). Treatment includes: surgical resection, radiation, and chemotherapy. This tumor is very responsive to chemotherapy regimens that include cisplatinum. [ NCIT:P378 ]
Term info
- DOID:1911 (MONDO:equivalentTo)
- EFO:0007252 (MONDO:equivalentTo)
- ICDO:9071/3 (NCIT:C3011)
- Orphanet:876 (MONDO:equivalentTo)
- MedDRA:10048251 (Orphanet:876/e)
- UMLS:C0014145 (Orphanet:876/e)
- NCIT:C3011 (MONDO:equivalentTo)
- ONCOTREE:BYST (MONDO:equivalentTo)
- SCTID:404081005 (MONDO:equivalentTo)
ordo_disease
http://identifiers.org/meddra/10048251
A non-seminomatous malignant germ cell tumor composed of primitive germ cells. It is the most common malignant germ cell tumor in the pediatric population. It occurs in the infant testis, ovary, sacrococcygeal region, vagina, uterus, prostate, abdomen, liver, retroperitoneum, thorax, and pineal/third ventricle. The tumor mimics the yolk sac of the embryo and produces alpha-fetoprotein (AFP). Treatment includes: surgical resection, radiation, and chemotherapy. This tumor is very responsive to chemotherapy regimens that include cisplatinum.
http://purl.obolibrary.org/obo/Orphanet_876, http://purl.obolibrary.org/obo/NCIT_C3011, http://identifiers.org/snomedct/404081005, http://purl.obolibrary.org/obo/DOID_1911, http://linkedlifedata.com/resource/umls/id/C0014145
yolk sac tumor, yolk SAC tumor, malignant, yolk Sac tumor, endodermal sinus neoplasm, yolk Sac tumour site unspecified, yolk Sac tumor site unspecified, endodermal sinus tumor, hepatoid yolk sac tumour, yolk Sac neoplasm
infantile embryonal carcinoma
MONDO:0005744