granular cell tumor
http://purl.obolibrary.org/obo/MONDO_0006235
An unusual benign or malignant neoplasm characterized by the presence of neoplastic large polygonal cells with granular, eosinophilic cytoplasm which contains abundant lysosomes. It was originally thought to be a tumor originating from muscle cells and was named granular cell myoblastoma. Subsequent studies have suggested a derivation from Schwann cells. It affects females more often than males and it usually presents as a solitary mass. A minority of patients have multiple tumors. It can arise from many anatomic sites including the posterior pituitary gland, skin, oral cavity, esophagus, stomach, heart, mediastinum, and breast. [ NCIT:C3474 ]
Term info
- EFO:1000284 (MONDO:equivalentTo)
- ONCOTREE:GCT (MONDO:equivalentTo)
- ICDO:9580/0 (NCIT:C3474)
- DOID:2411 (MONDO:equivalentTo)
- ICD9:215.9 (MONDO:relatedTo)
- UMLS:C0085167 (NCIT:C3474)
- MESH:D016586 (MONDO:equivalentTo)
- MESH:C535558 (MONDO:equivalentTo)
- NCIT:C3474 (MONDO:exact-label-match)
- SCTID:404035005 (MONDO:equivalentTo)
- GARD:0009618 (MONDO:equivalentTo)
gard_rare
Editor note: MESH considers this a myoblastoma but we go with NCIT which states nerve sheath origin, consistent with GARD definition; also check ONCOTREE placement
An unusual benign or malignant neoplasm characterized by the presence of neoplastic large polygonal cells with granular, eosinophilic cytoplasm which contains abundant lysosomes. It was originally thought to be a tumor originating from muscle cells and was named granular cell myoblastoma. Subsequent studies have suggested a derivation from Schwann cells. It affects females more often than males and it usually presents as a solitary mass. A minority of patients have multiple tumors. It can arise from many anatomic sites including the posterior pituitary gland, skin, oral cavity, esophagus, stomach, heart, mediastinum, and breast.
http://linkedlifedata.com/resource/umls/id/C0085167, http://identifiers.org/mesh/C535558, http://purl.obolibrary.org/obo/NCIT_C3474, http://identifiers.org/mesh/D016586, http://purl.obolibrary.org/obo/DOID_2411, http://identifiers.org/snomedct/404035005
granular cell myoblastoma, Abrikossoff's tumor, granular cell neoplasm, granular cell tumor (morphologic abnormality), granular cell tumor, Abrikossoff tumor, granular cell nerve sheath tumor, granular cell schwannoma
neoplasm of granular cell, granular cell tumor NOS (morphologic abnormality)
malignant variant of Abrikosov's tumor, Abrikosoff's granulous cell tumor, giant granulocellular Abrikosov's tumor, Abrikosov's tumor, Abrikosoff's tumor, GCT, Abrikosov’s tumor
MONDO:0006235
https://rarediseases.info.nih.gov/diseases/9618/granular-cell-tumor