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transient myeloproliferative syndrome

^ http://purl.obolibrary.org/obo/MONDO_0008040

A myeloid proliferation occurring in newborns with Down syndrome. It is clinically and morphologically indistinguishable from acute myeloid leukemia and is associated with GATA1 mutations. The blasts display morphologic and immunophenotypic features of megakaryocytic lineage. In the majority of patients the myeloid proliferation undergoes spontaneous remission. [ NCIT:P378 ]

Term info

database cross reference
  • NCIT:C82339 (MONDO:equivalentTo)
  • ONCOTREE:TAM (MONDO:equivalentTo)
  • SCTID:721307000 (MONDO:equivalentTo)
  • UMLS:C1834582 (Orphanet:420611)
  • OMIM:159595 (Orphanet:420611/e)
  • ICDO:9898/1 (NCIT:C82339)
  • GARD:0012765 (MONDO:equivalentTo)
  • Orphanet:420611 (OMIM:159595)
  • DOID:0060888 (MONDO:equivalentTo)
  • MESH:C563551 (MONDO:equivalentTo)
  • HP:0005534 (MONDO:otherHierarchy)
Subsets

ordo_disease

abbreviation
MST [ DOID:0060888 ]

abbreviation
TMD [ Orphanet:420611 ]

abbreviation
TAM [ DOID:0060888 ]

IAO 0000233

https://github.com/monarch-initiative/mondo/issues/4521

IAO 0000589

transient myeloproliferative syndrome (disease)

definition

A myeloid proliferation occurring in newborns with Down syndrome. It is clinically and morphologically indistinguishable from acute myeloid leukemia and is associated with GATA1 mutations. The blasts display morphologic and immunophenotypic features of megakaryocytic lineage. In the majority of patients the myeloid proliferation undergoes spontaneous remission.

exactMatch

http://purl.obolibrary.org/obo/NCIT_C82339, https://omim.org/entry/159595, http://purl.obolibrary.org/obo/DOID_0060888, http://purl.obolibrary.org/obo/Orphanet_420611, http://linkedlifedata.com/resource/umls/id/C1834582, http://identifiers.org/snomedct/721307000, http://identifiers.org/mesh/C563551

has exact synonym

transient myeloproliferative syndrome (disease), transient myeloproliferative disorder, TAM, transient myeloproliferative disease, transient myeloproliferative syndrome, TMD, leukemia, transient, of Down syndrome, transient abnormal myelopoiesis, Transient abnormal myelopoiesis associated with Down syndrome, transient leurkemia of Down syndrome, MST, transient leukemia

has related synonym

myeloproliferative syndrome, transient, leukemia, transient, Mst

id

MONDO:0008040