JSON

frontotemporal dementia

^ http://purl.obolibrary.org/obo/MONDO_0017276

Frontotemporal dementia (FTD) comprises a group of neurodegenerative disorders, characterized by progressive changes in behavior, executive dysfunction and language impairment, as a result of degeneration of the medial prefrontal and frontoinsular cortices. Four clinical subtypes have been identified: semantic dementia, progressive non-fluent aphasia, behavioral variant FTD and right temporal lobar atrophy. [ Orphanet:282 ]

Term info

database cross reference
  • DOID:9255 (MONDO:equivalentTo)
  • NCIT:C84719 (MONDO:equivalentTo)
  • UMLS:C0338451 (Orphanet:282/e)
  • MESH:D057180 (Orphanet:282/e)
  • UMLS:C0520716 (MONDO:equivalentTo)
  • MedDRA:10068968 (Orphanet:282/e)
  • GARD:0008436 (MONDO:equivalentTo)
  • Orphanet:282 (MONDO:equivalentTo)
Subsets

disease_grouping, ordo_group_of_disorders

abbreviation
MSTD [ GARD:0008436 ]

abbreviation
FTD [ Orphanet:282 ]

closeMatch

http://identifiers.org/meddra/10068968

definition

Frontotemporal dementia (FTD) comprises a group of neurodegenerative disorders, characterized by progressive changes in behavior, executive dysfunction and language impairment, as a result of degeneration of the medial prefrontal and frontoinsular cortices. Four clinical subtypes have been identified: semantic dementia, progressive non-fluent aphasia, behavioral variant FTD and right temporal lobar atrophy.

exactMatch

http://purl.obolibrary.org/obo/NCIT_C84719, http://identifiers.org/mesh/D057180, http://linkedlifedata.com/resource/umls/id/C0338451, http://purl.obolibrary.org/obo/Orphanet_282, http://linkedlifedata.com/resource/umls/id/C0520716, http://purl.obolibrary.org/obo/DOID_9255

excluded subClassOf

http://purl.obolibrary.org/obo/MONDO_0003996

has exact synonym

Wilhemsen-Lynch disease, multiple system tauopathy with presenile dementia, pallidopontonigral degeneration, FTD, frontotemporal lobar degeneration

has related synonym

frontotemporal lobe dementia (FLDEM), MSTD

id

MONDO:0017276