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oral submucous fibrosis

^ http://purl.obolibrary.org/obo/MONDO_0018166

Oral submucous fibrosis (OSMF) is a chronic, progressive disease that alters the fibroelasticity of the oral submucosa, prevalent in India and Southeast Asia but rare elsewhere, and characterized by burning and pain in the oral cavity, loss of gustatory sensation, the presence of blanched fibrous bands and stiffening of the oral mucosa and oro-pharynx (leading to trismus and a progressive reduction in mouth opening) and an increased risk of developing oral squamous cell cancer (3-19%). It is usually associated with the chewing of the areca nut (an ingredient in betel quid) but the exact etiology is unknown and there is currently no effective treatment. [ Orphanet:357154 ]

Term info

database cross reference
  • EFO:1001818 (MONDO:equivalentTo)
  • ICD10CM:K13.5 (Orphanet:357154/e)
  • MESH:D009914 (MONDO:equivalentTo)
  • UMLS:C0029172 (Orphanet:357154)
  • GARD:0007264 (MONDO:equivalentTo)
  • ICD9:528.8 (MONDO:i2s)
  • SCTID:32883009 (MONDO:equivalentTo)
  • DOID:5773 (MONDO:equivalentTo)
  • UMLS:C0029171 (NCIT:C34866)
  • Orphanet:357154 (MONDO:equivalentTo)
  • NCIT:C34866 (MONDO:equivalentTo)
Subsets

gard_rare, ordo_disease

abbreviation
OSMF [ Orphanet:357154 ]

definition

Oral submucous fibrosis (OSMF) is a chronic, progressive disease that alters the fibroelasticity of the oral submucosa, prevalent in India and Southeast Asia but rare elsewhere, and characterized by burning and pain in the oral cavity, loss of gustatory sensation, the presence of blanched fibrous bands and stiffening of the oral mucosa and oro-pharynx (leading to trismus and a progressive reduction in mouth opening) and an increased risk of developing oral squamous cell cancer (3-19%). It is usually associated with the chewing of the areca nut (an ingredient in betel quid) but the exact etiology is unknown and there is currently no effective treatment.

exactMatch

http://identifiers.org/snomedct/32883009, http://linkedlifedata.com/resource/umls/id/C0029171, http://purl.obolibrary.org/obo/NCIT_C34866, http://linkedlifedata.com/resource/umls/id/C0029172, http://purl.obolibrary.org/obo/Orphanet_357154, http://purl.obolibrary.org/obo/DOID_5773, http://purl.bioontology.org/ontology/ICD10CM/K13.5, http://identifiers.org/mesh/D009914

has exact synonym

oral cavity submucous fibrosis, oral submucosal fibrosis, including of tongue, oral submucosal fibrosis, OSMF

id

MONDO:0018166

seeAlso

https://rarediseases.info.nih.gov/diseases/7264/oral-submucous-fibrosis

Term relations