ALK-positive large B-cell lymphoma
Anaplastic lymphoma kinase (ALK)-positive diffuse large B-cell lymphoma is a very rare variant of diffuse large B-cell lymphoma (DLBCL) mainly affecting middle-aged immunocompetent men and characterized by a consistent primary involvement of lymph nodes (mainly in the cervical and mediastinum lymph nodes) and with infrequent extra nodal involvement of the bone marrow and other extra-nodal sites (head and neck region, liver, spleen, and gastrointestinal tract). It has an aggressive disease course, and is associated with a poor prognosis. [ Orphanet:364043 ]
Term info
- NCIT:C7225 (MONDO:exact-label-match)
- ICDO:9737/3 (NCIT:C7225)
- Orphanet:364043 (MONDO:equivalentTo)
- UMLS:C1333294 (NCIT:C7225)
- SCTID:715950008 (MONDO:equivalentTo)
ordo_disease
Anaplastic lymphoma kinase (ALK)-positive diffuse large B-cell lymphoma is a very rare variant of diffuse large B-cell lymphoma (DLBCL) mainly affecting middle-aged immunocompetent men and characterized by a consistent primary involvement of lymph nodes (mainly in the cervical and mediastinum lymph nodes) and with infrequent extra nodal involvement of the bone marrow and other extra-nodal sites (head and neck region, liver, spleen, and gastrointestinal tract). It has an aggressive disease course, and is associated with a poor prognosis.
http://purl.obolibrary.org/obo/NCIT_C7225, http://purl.obolibrary.org/obo/Orphanet_364043, http://identifiers.org/snomedct/715950008, http://linkedlifedata.com/resource/umls/id/C1333294
diffuse large B-cell lymphoma with expression of full-length ALK, ALK+ large B-cell lymphoma, ALK+ LBCL, ALK-positive large B-cell lymphoma, diffuse large B-cell lymphoma with expression of full-length anaplastic lymphoma kinase, ALK-DLBCL
MONDO:0018225