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ALK-positive large B-cell lymphoma

^ http://purl.obolibrary.org/obo/MONDO_0018225


Anaplastic lymphoma kinase (ALK)-positive diffuse large B-cell lymphoma is a very rare variant of diffuse large B-cell lymphoma (DLBCL) mainly affecting middle-aged immunocompetent men and characterized by a consistent primary involvement of lymph nodes (mainly in the cervical and mediastinum lymph nodes) and with infrequent extra nodal involvement of the bone marrow and other extra-nodal sites (head and neck region, liver, spleen, and gastrointestinal tract). It has an aggressive disease course, and is associated with a poor prognosis. [ Orphanet:364043 ]

Term info

database cross reference
  • NCIT:C7225 (MONDO:exact-label-match)
  • ICDO:9737/3 (NCIT:C7225)
  • Orphanet:364043 (MONDO:equivalentTo)
  • UMLS:C1333294 (NCIT:C7225)
  • SCTID:715950008 (MONDO:equivalentTo)
Subsets

ordo_disease

definition

Anaplastic lymphoma kinase (ALK)-positive diffuse large B-cell lymphoma is a very rare variant of diffuse large B-cell lymphoma (DLBCL) mainly affecting middle-aged immunocompetent men and characterized by a consistent primary involvement of lymph nodes (mainly in the cervical and mediastinum lymph nodes) and with infrequent extra nodal involvement of the bone marrow and other extra-nodal sites (head and neck region, liver, spleen, and gastrointestinal tract). It has an aggressive disease course, and is associated with a poor prognosis.

exactMatch

http://purl.obolibrary.org/obo/NCIT_C7225, http://purl.obolibrary.org/obo/Orphanet_364043, http://identifiers.org/snomedct/715950008, http://linkedlifedata.com/resource/umls/id/C1333294

has exact synonym

diffuse large B-cell lymphoma with expression of full-length ALK, ALK+ large B-cell lymphoma, ALK+ LBCL, ALK-positive large B-cell lymphoma, diffuse large B-cell lymphoma with expression of full-length anaplastic lymphoma kinase, ALK-DLBCL

id

MONDO:0018225

Term relations