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acute myeloid leukemia with t(8;16)(p11;p13) translocation

^ http://purl.obolibrary.org/obo/MONDO_0018256

A distinct form of Acute myeloid leukemia (AML) in which this chromosomal anomaly is found de novo or in therapy-related AML cases, and is characterized by frequent extramedullary involvement (mainly hepatomegaly, splenomegaly, lymphadenopathies, cutaneous infiltration, but also gum, bone, central nervous system, testicles involvement), severe coagulation disorder (disseminated intravascular coagulopathy or primary fibrinolysis) and poor prognosis. Morphologically, a blast population with a myelomonocytic stage of differentiation is observed. [ Orphanet:370026 ]

Term info

database cross reference
  • UMLS:C4511003 (MONDO:equivalentTo)
  • UMLS:CN204831 (MONDO:equivalentTo)
  • Orphanet:370026 (MONDO:equivalentTo)
  • SCTID:725390002 (MONDO:equivalentTo)
Subsets

ordo_disease

definition

A distinct form of Acute myeloid leukemia (AML) in which this chromosomal anomaly is found de novo or in therapy-related AML cases, and is characterized by frequent extramedullary involvement (mainly hepatomegaly, splenomegaly, lymphadenopathies, cutaneous infiltration, but also gum, bone, central nervous system, testicles involvement), severe coagulation disorder (disseminated intravascular coagulopathy or primary fibrinolysis) and poor prognosis. Morphologically, a blast population with a myelomonocytic stage of differentiation is observed.

exactMatch

http://linkedlifedata.com/resource/umls/id/C4511003, http://linkedlifedata.com/resource/umls/id/CN204831, http://identifiers.org/snomedct/725390002, http://purl.obolibrary.org/obo/Orphanet_370026

has exact synonym

AML with t(8;16)(p11;p13) translocation

id

MONDO:0018256

Term relations

Subclass of: