JSON

diffuse large B-cell lymphoma

^ http://purl.obolibrary.org/obo/MONDO_0018905


Diffuse large B-cell lymphoma is the most common subtype of non-Hodgkin lymphoma (NHL) in adults characterized by a median age of presentation in the sixth decade of life (but also rarely occurring in adolescents and children) with the initial presentation being single or multiple rapidly growing masses (that may or may not be painful) in nodal or extranodal sites (such as thyroid, skin, breast, gastrointestinal tract, testes, bone, or brain) and that can be accompanied by symptoms of fever, night sweats and weight loss. DLBCL has an aggressive disease course, with the elderly having a poorer prognosis than younger patients, and with relapses being common. [ Orphanet:544 ]

Term info

database cross reference
  • EFO:0000403 (MONDO:equivalentTo)
  • MedDRA:10012818 (Orphanet:544/e)
  • NCIT:C8851 (MONDO:equivalentTo)
  • MESH:D016403 (Orphanet:544/e)
  • Orphanet:544 (MONDO:equivalentTo)
  • GARD:0003178 (MONDO:equivalentTo)
  • DOID:0050745 (MONDO:equivalentTo)
  • ICDO:9680/3 (NCIT:C8851)
  • ICD9:200.7 (EFO:0000403)
  • UMLS:C0079744 (Orphanet:544/e)
Subsets

gard_rare, disease_grouping, ordo_group_of_disorders

abbreviation
DLBCL [ NCIT:C8851 Orphanet:544 ]

closeMatch

http://identifiers.org/meddra/10012818

definition

Diffuse large B-cell lymphoma is the most common subtype of non-Hodgkin lymphoma (NHL) in adults characterized by a median age of presentation in the sixth decade of life (but also rarely occurring in adolescents and children) with the initial presentation being single or multiple rapidly growing masses (that may or may not be painful) in nodal or extranodal sites (such as thyroid, skin, breast, gastrointestinal tract, testes, bone, or brain) and that can be accompanied by symptoms of fever, night sweats and weight loss. DLBCL has an aggressive disease course, with the elderly having a poorer prognosis than younger patients, and with relapses being common.

exactMatch

http://identifiers.org/mesh/D016403, http://purl.obolibrary.org/obo/DOID_0050745, http://purl.obolibrary.org/obo/NCIT_C8851, http://purl.obolibrary.org/obo/Orphanet_544, http://linkedlifedata.com/resource/umls/id/C0079744

has exact synonym

DLBCL, diffuse large B-cell lymphoma

id

MONDO:0018905

seeAlso

https://rarediseases.info.nih.gov/diseases/3178/diffuse-large-B-cell-lymphoma