JSON

Cushing syndrome

^ http://purl.obolibrary.org/obo/MONDO_0018912

Cushing's syndrome (CS) encompasses a group of hormonal disorders caused by prolonged and high exposure levels to glucocorticoids that can be of either endogenous (adrenal cortex production) or exogenous (iatrogenic) origin. [ Orphanet:553 ]

Term info

database cross reference
  • ICD10CM:E24 (MONDO:equivalentTo)
  • MESH:D000308 (Orphanet:553/e)
  • UMLS:C0010481 (Orphanet:553/e)
  • GARD:0006224 (MONDO:equivalentTo)
  • EFO:0003099 (MONDO:equivalentTo)
  • NCIT:C2969 (MONDO:equivalentTo)
  • MedDRA:10020610 (Orphanet:553/e)
  • Orphanet:553 (MONDO:equivalentTo)
  • MedDRA:10020562 (Orphanet:553/e)
  • ICD9:255.0 (EFO:0003099)
  • MedDRA:10020564 (Orphanet:553/e)
  • MESH:D003480 (Orphanet:553/e)
  • UMLS:C0001622 (Orphanet:553/e)
  • MedDRA:10011652 (Orphanet:553/e)
Subsets

disease_grouping, ordo_group_of_disorders

closeMatch

http://identifiers.org/meddra/10020564, http://identifiers.org/meddra/10020562, http://identifiers.org/meddra/10020610, http://identifiers.org/meddra/10011652

comment

Editor mote: DOID merged this into primary hyperaldosteronism but we believe this to be wrong. Update: fixed https://github.com/DiseaseOntology/HumanDiseaseOntology/issues/525; consider adding subclass for inherited form

definition

Cushing's syndrome (CS) encompasses a group of hormonal disorders caused by prolonged and high exposure levels to glucocorticoids that can be of either endogenous (adrenal cortex production) or exogenous (iatrogenic) origin.

exactMatch

http://purl.obolibrary.org/obo/NCIT_C2969, http://linkedlifedata.com/resource/umls/id/C0010481, http://purl.bioontology.org/ontology/ICD10CM/E24, http://purl.obolibrary.org/obo/Orphanet_553, http://identifiers.org/mesh/D003480

excluded subClassOf

http://purl.obolibrary.org/obo/MONDO_0006640

has broad synonym

hypercortisolism

has exact synonym

cortisol Excess, hyperadrenocorticism, Cushing syndrome, pituitary basophilism, Cushing's syndrome, suprarenogenic syndrome

has related synonym

nodular primary adrenocortical dysplasia, adrenal hyperfunction resulting from pituitary ACTH excess, ectopic adrenocorticotropic hormone syndrome

id

MONDO:0018912