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carcinoid heart disease

^ http://purl.obolibrary.org/obo/MONDO_0043529

Cardiac manifestation of gastrointestinal CARCINOID TUMOR that metastasizes to the liver. Substances secreted by the tumor cells, including SEROTONIN, promote fibrous plaque formation in ENDOCARDIUM and its underlying layers. These deposits cause distortion of the TRICUSPID VALVE and the PULMONARY VALVE eventually leading to STENOSIS and valve regurgitation. [ MESH:D002275 ]

Term info

database cross reference
  • EFO:1001775 (MONDO:equivalentTo)
  • SCTID:36222008 (MONDO:equivalentTo)
  • UMLS:C0007093 (MONDO:equivalentTo)
  • MESH:D002275 (MONDO:equivalentTo)
definition

Cardiac manifestation of gastrointestinal CARCINOID TUMOR that metastasizes to the liver. Substances secreted by the tumor cells, including SEROTONIN, promote fibrous plaque formation in ENDOCARDIUM and its underlying layers. These deposits cause distortion of the TRICUSPID VALVE and the PULMONARY VALVE eventually leading to STENOSIS and valve regurgitation.

exactMatch

http://identifiers.org/mesh/D002275, http://linkedlifedata.com/resource/umls/id/C0007093, http://identifiers.org/snomedct/36222008

has exact synonym

carcinoid heart disease

has related synonym

heart disease, carcinoid, carcinoid heart diseases, heart diseases, carcinoid

id

MONDO:0043529