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nodular lymphocyte predominant Hodgkin lymphoma

^ http://purl.obolibrary.org/obo/MONDO_0044778

A monoclonal B-cell neoplasm characterized by a nodular, or a nodular and diffuse proliferation of scattered large neoplastic cells known as popcorn or lymphocyte predominant cells (LP cells)- formerly called L&H cells for lymphocytic and/or histiocytic Reed-Sternberg cell variants. The LP cells lack CD15 and CD30 in nearly all instances. Patients are predominantly male, frequently in the 30-50 year age group. Most patients present with limited stage disease (localized peripheral lymphadenopathy, stage I or II). (WHO 2008) [ NCIT:C7258 ]

Term info

database cross reference
  • MEDGEN:233758 (UMLS:C1334968)
  • NCIT:C7258 (MONDO:equivalentTo)
  • ONCOTREE:NLPHL (MONDO:equivalentTo)
  • UMLS:C1334968 (Orphanet:86893/e)
  • Orphanet:86893 (MONDO:equivalentTo)
abbreviation
NLPHL [ NCIT:C7258 Orphanet:86893 ]

closeMatch

http://identifiers.org/medgen/233758

definition

A monoclonal B-cell neoplasm characterized by a nodular, or a nodular and diffuse proliferation of scattered large neoplastic cells known as popcorn or lymphocyte predominant cells (LP cells)- formerly called L&H cells for lymphocytic and/or histiocytic Reed-Sternberg cell variants. The LP cells lack CD15 and CD30 in nearly all instances. Patients are predominantly male, frequently in the 30-50 year age group. Most patients present with limited stage disease (localized peripheral lymphadenopathy, stage I or II). (WHO 2008)

exactMatch

http://purl.obolibrary.org/obo/Orphanet_86893, http://purl.obolibrary.org/obo/NCIT_C7258, http://linkedlifedata.com/resource/umls/id/C1334968

has exact synonym

nodular lymphocyte predominant Hodgkin lymphoma, NLPHL, nodular lymphocyte-predominant Hodgkin lymphoma, Hodgkin lymphoma nodular lymphocyte predominant type, NOS, Hodgkin lymphoma nodular LP, NOS, nodular lymphocyte predominant Hodgkin's lymphoma

id

MONDO:0044778